With a cure for the Red Virus and the goal to save the human race, Navy Captain Tom Chandler and his crew return to the States unsure of what they will find. As the crew seeks to find survivors and their families, they encounter a new, emerging enemy who's vying for control and may hinder the mass production of the cure.

Based on William Brinkley's popular novel, it chronicles a global catastrophe that nearly decimates the world's population. Because of its positioning, the Navy destroyer U.S.S. Nathan James avoided falling victim to the devastating tragedy. But now the crew and its captain must confront the reality of their new existence in a world where they may be among the few remaining survivors.