A.J. and his friends are afraid that Ms. Todd, their substitute teacher, has killed their regular teacher and is trying to take over her job.

Fifth period is hands down the best time of day in Connor U. Eubanks Middle School, because that's when Mr. Lewis teaches Jazz Lab. So his students are devastated when their beloved teacher quits abruptly. Once they make a connection between budget cuts and Mr. Lewis's disappearance, they hatch a plan: stop the cuts, save their class. Soon, they become an unlikely band of crusaders, and their quest quickly snowballs into something much bigger--a movement...

Although excited at the prospect of a fancy class trip to the art museum, the bumpy bus ride to get there leaves Nancy feeling anything but fancy.

When her teacher announces that he is getting married, Lilly the mouse sets her heart on being the flower girl at his wedding.

Mr. Docker, a new science teacher, is a crazy inventor who blows things up, uses potatoes for power, and has A.J. and his friends wondering whether science is for nerds or is the coolest subject ever.

The notorious Miss Swamp reappears at the Horace B. Smedley School, this time to shape up the football team and make them win at least one game.

It's almost summer vacation and the students in room 2B are having trouble concentrating on their butterfly project, until a frightening-looking new teacher comes to supervise the Suspension Room and Harry is sent there as punishment for unruly behavior.

A student wonders why her teacher has chosen to teach in her school for so long, and highlights all the special things her teacher does for her class.

The students of Diffendoofer School celebrate their unusual teachers and curriculum, including Miss Fribble who teaches laughing, Miss Bonkers who teaches frogs to dance, and Mr. Katz who builds robotic rats.

Lilly loves everything about school, especially her teacher, but when he asks her to wait a while before showing her new purse, she does something for which she is very sorry later.