George and Harold, and their doubles, Yesterday George and Yesterday Harold, have a good thing going. Two of them go to school, while the other two hide in the tree house and play video games all day-then they switch! But when their malicious gym teacher, Mr Meaner, creates a method of mind control that turns their fellow students into attentive, obedient, perfect children, the future of all humanity will be in their hands!

Principal Krupp once again turns into the superhero Captain Underpants in order to save the world, and Jerome Horwitz Elementary School, from the evil talking toilets and the Turbo Toilet 2000.

The monstrous Turbo Toilet 2000 is determined to take revenge on George, Harold, and Captain Underpants. El Inodoro Turbotron 2000 vuelve a atacar. El tazon

Only Captain Underpants can stop the three evil space aliens who have invaded Jerome Horwitz Elementary School and turned everyone into lunchroom zombie nerds. Derroto al diabolico DR. Panal textermino alos terribles inodoros parlantes..Y ahora lucha por su vida.

A snotty situation ensues when Melvin Sneedley, an academically gifted student, turns into the Bionic Booger Boy and must be stopped by George, Harold, and Captain Underpants.

George and Harold and their doubles, Yesterday George and Yesterday Harold, have been taking turns going to school, but when the doubles fall prey to their gym teacher, Mr. Meaner, and his method of mind control that turns students into attentive, obedient, perfect children, it is up to original George and Harold to strike back. Jorge, Berto y sus dobles, Jorge y Berto de Ayer, la están pasando muy bien. Dos de ellos van a la escuela mientras los...

Jorge y Beto crean al mejor superh?roe de la historia de su escuela, y despu?s, hacen que cobre vida. When George and Harold hypnotize their principal into thinking that he is the superhero Captain Underpants, he leads them to the lair of the nefarious Dr. Diaper, where they must defeat his evil robot henchmen.